Drugs / aPHAD-SE
last change May 2026 re-read 3 minutes ago

aPHAD-SE

Other / unclassified targets TLR4 via activation

Trials 0

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Comparator or background therapy1 trial
Phase 1 NCT06546709 Background Jan 2025 → May 2026 overdue Lassa fever Wilbur Chen, MD, MS Active not recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as aPHAD-SE ClinicalTrials.gov intervention name — accepted as the source's own label NCT06546709 ↗
Action Activate “TLR-4)-activating oil-in-water emulsion adjuvant” NCT06546709 ↗
Modality Other / unclassified “3D-(6- acyl) Phosphorylated Hexaacyl Disaccharides (PHAD)-Stable squalene oil-in-water nanoemulsion (aPHAD-SE) adjuvant administered by IM injection” NCT06546709 ↗
Route Intramuscular “Rabies-Vectored Monovalent Lassa Fever Vaccine (LASSARAB) with 3D-(6- acyl) Phosphorylated Hexaacyl Disaccharides (PHAD)-Stable squalene oil-in-water nanoemulsion (aPHAD-SE)...” NCT06546709 ↗
Target TLR4 “toll-like receptor (TLR-4)-activating oil-in-water emulsion adjuvant” NCT06546709 ↗