Drugs / briciclib
last change Dec 2015 re-read 3 minutes ago

briciclib

also known as BRICICLIB SODIUM · ON 013105 · ON 014185

Small molecule targets CCND1 via inhibition

Developed for
acute lymphoblastic leukemia · neoplasm
Investigated by
Traws Pharma, Inc.

Trials 2

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02168725 Jun 2014 → Dec 2015 neoplasm Traws Pharma, Inc. Terminated No outcome recorded
Phase 1 NCT01049113 Nov 2009 → Dec 2014 acute lymphoblastic leukemia Traws Pharma, Inc. Terminated No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as briciclib ClinicalTrials.gov intervention name — accepted as the source's own label NCT02168725 ↗
Known as BRICICLIB SODIUM ChEMBL registry synonym — accepted as the source's own label CHEMBL1206245 ↗
Known as ON 013105 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01049113 ↗
Known as ON 014185 ChEMBL registry synonym — accepted as the source's own label CHEMBL1206245 ↗
Action Inhibit “G1/S-specific cyclin D1 inhibitor” CHEMBL1206245 ↗
Modality Small molecule — CHEMBL1206245 ↗
Route Intravenous “2-hour intravenous infusion once a week.” NCT01049113 ↗
Target CCND1 “G1/S-specific cyclin D1 inhibitor” CHEMBL1206245 ↗