Drugs / Mutant-CALR peptides
last change Apr 2023 re-read 2 minutes ago

Mutant-CALR peptides

Vaccine

Developed for
essential thrombocythemia · myelofibrosis
Investigated by
Marina Kremyanskaya

Trials 1 · a red edge is where a trial was stopped

2024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05025488 Apr 2023 → Mar 2027 expected essential thrombocythemia, myelofibrosis Marina Kremyanskaya Recruiting No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as Mutant-CALR peptides “ten (10) doses of Mutant-CALR peptides with KLH as helper peptide (in the first vaccine only).” NCT05025488
Action Deplete “target and eliminate CALR+ malignant cells” NCT05025488
Modality Vaccine “peptide-based vaccineNCT05025488