Drugs / Atirmociclib

Trials 18 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 19 trials
Phase 1 NCT07677358 Jul 2026 → Aug 2027 expected liver disorder Pfizer Not yet recruiting No outcome recorded
Phase 1 NCT07215078 Oct 2025 → Jun 2026 overdue Pfizer Recruiting No outcome recorded
Phase 1 NCT07160738 Sep → Nov 2025 Pfizer Completed No outcome recorded
Phase 1 NCT07130097 Aug → Oct 2025 Pfizer Completed No outcome recorded
Phase 1 NCT06897683 Mar → May 2025 Pfizer Completed No outcome recorded
Phase 1 NCT06267963 Jan → Apr 2024 Pfizer Completed No outcome recorded
Phase 1 NCT05923411 Jul 2023 → Jun 2024 Pfizer Completed No outcome recorded
Phase 1 NCT05508906 Aug 2022 → Dec 2027 expected Her2-receptor negative breast cancer, estrogen-receptor positive breast cancer, female breast carcinoma, metastatic malignant neoplasm Olema Pharmaceuticals, Inc. Recruiting No outcome recorded
Phase 1 NCT05216432 Dec 2021 → Apr 2027 expected Her2-receptor negative breast cancer, PIK3CA-related overgrowth spectrum Relay Therapeutics, Inc. Recruiting No outcome recorded
Phase 1/23 trials
Phase 1/2 NCT06206837 Feb 2024 → Sep 2025 overdue breast cancer Pfizer Active not recruiting No outcome recorded
Phase 1/2 NCT05262400 Mar 2022 → Aug 2026 overdue breast cancer Pfizer Active not recruiting No outcome recorded
Phase 1/2 NCT03424005 Mar 2018 → Sep 2030 expected breast cancer Hoffmann-La Roche Recruiting No outcome recorded
Phase 25 trials
Phase 2 NCT07427394 May 2026 → Dec 2027 expected female breast carcinoma AstraZeneca Recruiting No outcome recorded
Phase 2 NCT06465368 Jul 2024 → Jul 2025 breast cancer Pfizer Completed No outcome recorded
Phase 2 NCT06105632 Jan 2024 → Jan 2026 overdue breast cancer Pfizer Active not recruiting No outcome recorded
Phase 2 NCT04606446 Nov 2020 → Jul 2029 expected breast cancer, castration-resistant prostate carcinoma, non-small cell lung carcinoma Pfizer Recruiting No outcome recorded
Phase 2 NCT04557449 Sep 2020 → Sep 2026 expected breast neoplasm, liposarcoma, lung adenocarcinoma, prostate cancer Pfizer Active not recruiting No outcome recorded
Phase 31 trial
Phase 3 NCT06760637 Jan 2025 → Jan 2029 expected breast cancer Pfizer Active not recruiting No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT06239467 Background Feb 2024 → Dec 2026 expected breast cancer OnKure, Inc. Active not recruiting No outcome recorded

Press releases naming this drug 1 release

DateIssuerRelease
2026-03-17 Pfizer Pfizer Announces Positive Topline Phase 2 Results for Next-Generation CDK4 Inhibitor, Atirmociclib, in Second-Line Metastatic Breast Cancer pfizer.com

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 20 sources stand behind the page.

FieldValueCited text
Known as Atirmociclib ClinicalTrials.gov intervention name — accepted as the source's own label NCT05508906
5

NCT06239467

NCT07427394

NCT07677358

NCT03424005

NCT07215078

Known as PF-07220060 “atirmociclib (PF-07220060)” NCT07215078
13

NCT06465368

NCT07130097

NCT06206837

NCT06105632

NCT05216432

NCT05923411

NCT06760637

NCT06267963

NCT07160738

NCT04557449

NCT04606446

NCT05262400

NCT06897683

Action Inhibit “CDK4 inhibitor” NCT04557449
Modality Small molecule CHEMBL5187755
Route Oral “Atirmociclib administered orally” NCT03424005
Target CDK4 CDK4 inhibitor” NCT04557449