Drugs / Talarozole
last change Dec 2007 re-read 2 minutes ago

Talarozole

also known as R-115866 · Rambazole · Talarozol

Small molecule targets CYP26A1 via inhibition

Developed for
acne · psoriasis · dermatitis
Investigated by
Stiefel, a GSK Company

Trials 2 · a red edge is where a trial was stopped

200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT00725439 Sep 2004 → Jul 2005 acne Stiefel, a GSK Company Completed No outcome recorded
Phase 2 NCT00725348 Apr 2004 → Mar 2005 psoriasis Stiefel, a GSK Company Completed No outcome recorded
Also used as a comparator or background therapy in 2 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00719121 Comparator Nov → Dec 2006 dermatitis Stiefel, a GSK Company Completed No outcome recorded
Phase 21 trial
Phase 2 NCT00716144 Comparator Jun 2006 → May 2007 psoriasis Stiefel, a GSK Company Completed No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Talarozole ClinicalTrials.gov intervention name — accepted as the source's own label NCT00719121
3

NCT00725439

NCT00725348

NCT00716144

Known as R-115866 ChEMBL registry synonym — accepted as the source's own label CHEMBL459505
Known as Rambazole ChEMBL registry synonym — accepted as the source's own label CHEMBL459505
Known as Talarozol ChEMBL registry synonym — accepted as the source's own label CHEMBL459505
Action Inhibit “Cytochrome P450 26A1 inhibitor” CHEMBL459505
Modality Small molecule CHEMBL459505
Route Oral Oral Capsule Once Daily” NCT00716144
Target CYP26A1 “Cytochrome P450 26A1 inhibitor” CHEMBL459505