Drugs / Talarozole
last change Dec 2007 re-read 9 days ago

Talarozole

also known as R-115866 · Rambazole · Talarozol

Small molecule targets CYP26A1 via inhibition

Developed for
acne · psoriasis · dermatitis
Investigated by
Stiefel, a GSK Company

Trials 2

200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 22 trials
Phase 2 NCT00725439 Sep 2004 → Jul 2005 acne Stiefel, a GSK Company Completed No outcome recorded
Phase 2 NCT00725348 Apr 2004 → Mar 2005 psoriasis Stiefel, a GSK Company Completed No outcome recorded
Comparator or background therapy2 trials
Phase 1 NCT00719121 Comparator Nov → Dec 2006 dermatitis Stiefel, a GSK Company Completed No outcome recorded
Phase 2 NCT00716144 Comparator Jun 2006 → May 2007 psoriasis Stiefel, a GSK Company Completed No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Talarozole ClinicalTrials.gov intervention name — accepted as the source's own label NCT00716144 ↗
3

NCT00719121 ↗

NCT00725439 ↗

NCT00725348 ↗

Known as R-115866 ChEMBL registry synonym — accepted as the source's own label CHEMBL459505 ↗
Known as Rambazole ChEMBL registry synonym — accepted as the source's own label CHEMBL459505 ↗
Known as Talarozol ChEMBL registry synonym — accepted as the source's own label CHEMBL459505 ↗
Action Inhibit “Cytochrome P450 26A1 inhibitor” CHEMBL459505 ↗
Modality Small molecule — CHEMBL459505 ↗
Route Oral “Oral Capsule Once Daily” NCT00716144 ↗
Target CYP26A1 “Cytochrome P450 26A1 inhibitor” CHEMBL459505 ↗