Drugs / GSK239512
last change Sep 2014 re-read 2 minutes ago

GSK239512

also known as GSK-239512A

Small molecule targets HRH3 via inhibition

Developed for
Alzheimer disease · relapsing-remitting multiple sclerosis · schizophrenia
Investigated by
GlaxoSmithKline

Trials 5 · a red edge is where a trial was stopped

200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT00675090 Feb 2008 → Jun 2009 Alzheimer disease GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT00474513 Mar 2007 → Mar 2008 cognitive impairment with or without cerebellar ataxia, dementia GlaxoSmithKline Completed No outcome recorded
Phase 23 trials
Phase 2 NCT01772199 Feb 2013 → Sep 2014 relapsing-remitting multiple sclerosis GlaxoSmithKline Completed No outcome recorded
Phase 2 NCT01009060 Dec 2009 → Aug 2011 schizophrenia GlaxoSmithKline Completed No outcome recorded
Phase 2 NCT01009255 Nov 2009 → Nov 2010 Alzheimer disease GlaxoSmithKline Completed No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT01802931 Comparator Jan → Apr 2013 multiple sclerosis GlaxoSmithKline Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as GSK239512 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00474513
5

NCT01009255

NCT01009060

NCT01802931

NCT01772199

NCT00675090

Known as GSK-239512A ChEMBL registry synonym — accepted as the source's own label CHEMBL3092650
Action Inhibit “GSK239512, a Histamine H3 Antagonist” NCT00474513
1

“Histamine H3 receptor antagonist” CHEMBL3092650

Modality Small molecule CHEMBL3092650
Route Oral “after receiving an oral dose of the drug” NCT00474513
Target HRH3 “Histamine H3 receptor antagonist” CHEMBL3092650