Drugs / PELITREXOL
last change Nov 2004 re-read 3 minutes ago

PELITREXOL

also known as AG-2037

Small molecule targets GART via inhibition

Developed for
cancer of unknown primary site · colorectal cancer · lung neoplasm
Investigated by
Pfizer · National Cancer Institute (NCI) · University of Alabama at Birmingham

Trials 3

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00017524 Mar 2001 → Nov 2004 cancer of unknown primary site University of Alabama at Birmingham Completed No outcome recorded
Phase 22 trials
Phase 2 NCT00090701 Sep 2004 → ? lung neoplasm Pfizer Withdrawn No outcome recorded
Phase 2 NCT00078468 Dec 2003 → Sep 2004 colorectal cancer Pfizer Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as PELITREXOL ClinicalTrials.gov intervention name — accepted as the source's own label NCT00078468 ↗
1

NCT00017524 ↗

Known as AG-2037 “PELITREXOL/AG-2037” NCT00078468 ↗
1

NCT00090701 ↗

Action Inhibit “GAR transformylase inhibitor” CHEMBL2107361 ↗
1

“GARFT Inhibitor AG2037” NCT00078468 ↗

Modality Small molecule — CHEMBL2107361 ↗
Target GART “GAR transformylase inhibitor” CHEMBL2107361 ↗