Drugs / LEQ506
last change Jun 2015 re-read 3 minutes ago

LEQ506

also known as NVP-LEQ506

Small molecule targets SMO via inhibition

Developed for
medulloblastoma · skin basal cell carcinoma
Investigated by
Novartis Pharmaceuticals

Trials 1

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT01106508 Oct 2010 → Jun 2015 medulloblastoma, skin basal cell carcinoma Novartis Pharmaceuticals Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as LEQ506 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01106508 ↗
Known as NVP-LEQ506 ChEMBL registry synonym — accepted as the source's own label CHEMBL3133037 ↗
Action Inhibit “Smoothened homolog antagonist” CHEMBL3133037 ↗
Modality Small molecule — CHEMBL3133037 ↗
Route Oral “LEQ506 given orally on a daily dosing schedule” NCT01106508 ↗
Target SMO “Smoothened homolog antagonist” CHEMBL3133037 ↗