Drugs / CD19/CD22 bispecific CAR-T cells
last change Apr 2026 re-read 3 minutes ago

CD19/CD22 bispecific CAR-T cells

also known as CAR2219

Cell therapy targets CD19, CD22 via depletion

Developed for
large B-cell lymphoma
Investigated by
Beijing Tongren Hospital

Trials 1

20222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT07461831 Feb 2022 → Apr 2026 overdue large B-cell lymphoma Beijing Tongren Hospital Active not recruiting No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as CD19/CD22 bispecific CAR-T cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT07461831 ↗
Known as CAR2219 “In this prospective study, the investigators aimed to evaluate the efficacy and safety of CD19/CD22 bispecific CAR-T cell (CAR2219) therapy in patients with R/R LBCL.” NCT07461831 ↗
Action Deplete “enabling precise elimination of tumor cells.” NCT07461831 ↗
Modality Cell therapy “Chimeric antigen receptor-T (CAR-T) cell therapy involves genetically engineering T cells to express chimeric antigen receptors (CARs)” NCT07461831 ↗
Route Other “CD19/CD22-bispecific CAR-T cells were infused at the dosage of 2×10e6/kg” NCT07461831 ↗
Target CD19 “targeting both CD19 and CD22” NCT07461831 ↗
Target CD22 “targeting both CD19 and CD22” NCT07461831 ↗