Drugs / CNTO 3157
last change Jul 2017 re-read 3 minutes ago

CNTO 3157

Monoclonal antibody targets TLR3 via inhibition

Developed for
asthma
Investigated by
Janssen Research & Development, LLC · Centocor, Inc.

Trials 3

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02008279 Dec 2013 → Aug 2014 — Janssen Research & Development, LLC Completed No outcome recorded
Phase 1 NCT01704040 Oct 2012 → Nov 2014 — Janssen Research & Development, LLC Completed Missed primary
Phase 1 NCT01195207 Jun 2010 → Jan 2012 asthma Centocor, Inc. Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as CNTO3157 “We sought to evaluate an inhibitory mAb to Toll-like receptor 3, CNTO3157, on experimental HRV-16 inoculation in healthy subjects and asthmatic patients.” PMID 28734844 ↗ Jul 2017
3

NCT01704040 ↗

NCT02008279 ↗

NCT01195207 ↗

Action Inhibit “We sought to evaluate an inhibitory mAb to Toll-like receptor 3, CNTO3157, on experimental HRV-16 inoculation in healthy subjects and asthmatic patients.” PMID 28734844 ↗ Jul 2017
Modality Monoclonal antibody “We sought to evaluate an inhibitory mAb to Toll-like receptor 3, CNTO3157, on experimental HRV-16 inoculation in healthy subjects and asthmatic patients.” PMID 28734844 ↗ Jul 2017
Route Intravenous “CNTO 3157 will be administered by IV infusion.” NCT01195207 ↗
Target TLR3 “We sought to evaluate an inhibitory mAb to Toll-like receptor 3, CNTO3157, on experimental HRV-16 inoculation in healthy subjects and asthmatic patients.” PMID 28734844 ↗ Jul 2017