Drugs / RX-518
last change Jun 2022 re-read 3 minutes ago

RX-518

also known as CK-101 · Olafertinib

Small molecule targets EGFR via inhibition

Developed for
non-small cell lung carcinoma
Investigated by
Checkpoint Therapeutics, Inc.

Trials 1

20172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02926768 Sep 2016 → Sep 2020 adenocarcinoma, non-small cell lung carcinoma Checkpoint Therapeutics, Inc. Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as RX-518 ChEMBL registry synonym — accepted as the source's own label CHEMBL4297486 ↗
Known as CK-101 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02926768 ↗
Known as Olafertinib ChEMBL registry synonym — accepted as the source's own label CHEMBL4297486 ↗
Action Inhibit “CK-101 is a novel, potent, small molecule tyrosine kinase inhibitor (TKI) that selectively targets mutant forms of the epidermal growth factor receptor (EGFR) while sparing...” NCT02926768 ↗
Modality Small molecule “CK-101 is a novel, potent, small molecule tyrosine kinase inhibitor (TKI)” NCT02926768 ↗
Route Oral “oral CK-101 administered daily” NCT02926768 ↗
Target EGFR “selectively targets mutant forms of the epidermal growth factor receptor (EGFR)” NCT02926768 ↗