Drugs / LY3537021
last change Dec 2025 re-read 2 minutes ago

LY3537021

targets GIPR via activation

Developed for
type 2 diabetes mellitus
Investigated by
Eli Lilly and Company

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT05444569 Aug 2022 → Feb 2023 Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT04586907 Nov 2020 → Nov 2021 type 2 diabetes mellitus Eli Lilly and Company Completed No outcome recorded
Phase 21 trial
Phase 2 NCT07169851 Nov 2025 → Dec 2026 expected neoplasm Eli Lilly and Company Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as LY3537021 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05444569
2

NCT07169851

NCT04586907

Action Activate “long-acting GIPR agonist LY3537021” PMID 41391569 Dec 2025
Route Subcutaneous “There was no delay in gastric emptying following a single subcutaneous dose of 0.3-25 mg LY3537021.” PMID 41391569 Dec 2025
Target GIPR “In vitro, LY3537021 demonstrated potency greater than native GIP and selectivity for the GIPR.” PMID 41391569 Dec 2025