drugset
Drugs / Felbamate
last change Dec 2013 re-read 2 minutes ago

Felbamate

also known as ADD-03055 · Felbamato · Felbatol · Felbatol (Registered Trademark) · NSC-759866 · Taloxa · W-554

Small molecule

Developed for
bipolar disorder · epilepsy
Investigated by
National Institute of Mental Health (NIMH)

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) FELBATOL — 1993-07-29 fda.gov ↗

Trials 1 · a red edge is where a trial was stopped

today
US approved 1993
NCT00034229 · Ph 2
19931994199519961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT00034229 Apr 2002 → Mar 2006 bipolar disorder National Institute of Mental Health (NIMH) Completed No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 4 NCT00552526 Comparator Nov 2007 → Jan 2011 epilepsy Oslo University Hospital Unknown No outcome recorded

Evidence & citations 10 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Felbamate “Drugs from ACT groups N03A, N05BA, N05CD, H02A or S01EC will be used including prednisolon,levetiracetam, valproate, carbamazepine, oxcarbazepine, topiramate, felbamate,...” NCT00552526 ↗
1

NCT00034229 ↗
Known as ADD-03055 ChEMBL registry synonym — accepted as the source's own label CHEMBL1094 ↗
Known as Felbamato ChEMBL registry synonym — accepted as the source's own label CHEMBL1094 ↗
Known as Felbatol ChEMBL registry synonym — accepted as the source's own label CHEMBL1094 ↗
Known as Felbatol (Registered Trademark) “Felbamate (Felbatol ® (Registered Trademark)) a dicarbamate, is FDA-approved as monotherapy and adjunctive therapy in adults with partial-onset seizures” NCT00034229 ↗
Known as NSC-759866 ChEMBL registry synonym — accepted as the source's own label CHEMBL1094 ↗
Known as Taloxa ChEMBL registry synonym — accepted as the source's own label CHEMBL1094 ↗
Known as W-554 ChEMBL registry synonym — accepted as the source's own label CHEMBL1094 ↗
Action Inhibit “reduces glutamatergic throughput via inhibition of glutamate release and NMDA, AMPA, and metabotropic glutamate receptor blockade” NCT00034229 ↗
Modality Small molecule “a dicarbamate” NCT00034229 ↗