Drugs / GSK2696273
last change Jun 2019 re-read 3 minutes ago

GSK2696273

targets ADA via restoration

Developed for
immunodeficiency disease
Investigated by
Fondazione Telethon

Trials 1

2003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT00598481 Oct 2002 → Jul 2011 immunodeficiency disease Fondazione Telethon Completed Met primary

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as GSK2696273 “GSK2696273 (autologous CD34+ cells transduced with retroviral vector that encodes for the human adenosine deaminase [ADA] enzyme) is a gamma-retroviral ex vivo gene therapy” PMID 28319446 ↗ Mar 2017
Action Restore “partial to full correction of ADA expression” PMID 19652199 ↗ Aug 2009
Target ADA “encodes for the human adenosine deaminase [ADA] enzyme” PMID 28319446 ↗ Mar 2017