Drugs / Denikitug
last change Jul 2026 re-read 2 minutes ago

Denikitug

also known as DEN

Monoclonal antibody targets CCR8

Developed for
colorectal cancer · esophageal adenocarcinoma · gastric adenocarcinoma · gastroesophageal junction adenocarcinoma · Her2-receptor negative breast cancer · neoplasm
Investigated by
Gilead Sciences

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT05007782 Aug 2021 → Dec 2028 expected neoplasm Gilead Sciences Recruiting No outcome recorded
Phase 22 trials
Phase 2 NCT07546812 Jul 2026 → Jan 2030 expected Her2-receptor negative breast cancer, esophageal adenocarcinoma, gastric adenocarcinoma, gastroesophageal junction adenocarcinoma Gilead Sciences Recruiting No outcome recorded
Phase 2 NCT07527858 May 2026 → Dec 2028 expected colorectal cancer Gilead Sciences Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Denikitug ClinicalTrials.gov intervention name — accepted as the source's own label NCT05007782
2

NCT07527858

NCT07546812

Known as DEN “study drug, Denikitug (DEN, GS-1811)” NCT07546812
Modality Monoclonal antibody “an Afucosylated Anti-CCR8 Monoclonal AntibodyNCT05007782
Route Intravenous “Administered Intravenously” NCT05007782
Target CCR8 “Anti-CCR8NCT05007782