INDIGOTINDISULFONATE

also known as Indigo Carmine · Indigotindisulfonate sodium · Acid blue 74 · Bleu covalac w 6504 · Bludigo · C.i. 73015 · C.i. 75781 · C.i. acid blue 74 · +9 more

Small molecule

Investigated by: Prove pharm · Hillel Yaffe Medical Center · VA Office of Research and Development

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

Milestone	Jurisdiction	Brand	Indication	Date	Sentence it was read from
Approved	US (FDA)	BLUDIGO	—	2022-07-08	fda.gov ↗

Trials 5

today

US approved 2022

NCT06448143 · Ph 3 NCT06085183 · Ph 4 NCT06054880 · Ph 4 NCT01914445 · not/applicable NCT01607255 · Ph 4

201320142015201620172018201920202021202220232024202520262027

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 31 trial
Phase 3	NCT06448143	Jan → Dec 2026 expected	ureteral disorder	Prove pharm	Not yet recruiting	No outcome recorded
Phase 43 trials
Phase 4	NCT06085183	Dec 2023 → Jun 2026 overdue	ureteral disorder	Prove pharm	Recruiting	No outcome recorded
Phase 4	NCT06054880	Oct 2023 → Jan 2026 overdue	ureteral disorder	Prove pharm	Recruiting	No outcome recorded
Phase 4	NCT01607255	May 2013 → Jun 2017	colorectal neoplasm	VA Office of Research and Development	Completed	No outcome recorded
Phase not applicable1 trial
—	NCT01914445	Aug → Dec 2013	inflammatory bowel disease	Hillel Yaffe Medical Center	Unknown	No outcome recorded
Comparator or background therapy1 trial
Phase 1	NCT01901510 Comparator	May 2013 → Jul 2014	polyp of colon	Mayo Clinic	Completed	No outcome recorded

Press releases naming this drug 1 release

Date	Issuer	Release
2022-07-12	Prove pharm	Provepharm obtient l’accord de la FDA pour commercialiser BLUDIGO, son carmin d’indigo injectable provepharm.com ↗

Evidence & citations 21 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

Field	Value	Cited text
Known as	INDIGOTINDISULFONATE	ChEMBL registry synonym — accepted as the source's own label CHEMBL1091250 ↗
Known as	Acid blue 74	ChEMBL registry synonym — accepted as the source's own label CHEMBL1091250 ↗
Known as	Bleu covalac w 6504	ChEMBL registry synonym — accepted as the source's own label CHEMBL1091250 ↗
Known as	Bludigo	ChEMBL registry synonym — accepted as the source's own label CHEMBL1091250 ↗
Known as	C.i. 73015	ChEMBL registry synonym — accepted as the source's own label CHEMBL1091250 ↗
Known as	C.i. 75781	ChEMBL registry synonym — accepted as the source's own label CHEMBL1091250 ↗
Known as	C.i. acid blue 74	ChEMBL registry synonym — accepted as the source's own label CHEMBL1091250 ↗
Known as	C.i.food blue 1	ChEMBL registry synonym — accepted as the source's own label CHEMBL1091250 ↗
Known as	CI-(1975)NO.73015	ChEMBL registry synonym — accepted as the source's own label CHEMBL1091250 ↗
Known as	E-132	ChEMBL registry synonym — accepted as the source's own label CHEMBL1091250 ↗
Known as	Gardenia grun p-ac-8	ChEMBL registry synonym — accepted as the source's own label CHEMBL1091250 ↗
Known as	Holunder p-ac-5	ChEMBL registry synonym — accepted as the source's own label CHEMBL1091250 ↗
Known as	Indigo Carmine	ClinicalTrials.gov intervention name — accepted as the source's own label NCT01914445 ↗ 2 NCT01901510 ↗ NCT01607255 ↗
Known as	Indigotindisulfonate sodium	ClinicalTrials.gov intervention name — accepted as the source's own label NCT06448143 ↗ 2 NCT06085183 ↗ NCT06054880 ↗
Known as	Indigotindisulphonate sodium	ChEMBL registry synonym — accepted as the source's own label CHEMBL1091250 ↗
Known as	Indigotine 85%	ChEMBL registry synonym — accepted as the source's own label CHEMBL1091250 ↗
Known as	INS NO.132	ChEMBL registry synonym — accepted as the source's own label CHEMBL1091250 ↗
Known as	INS-132	ChEMBL registry synonym — accepted as the source's own label CHEMBL1091250 ↗
Modality	Diagnostic / imaging agent	“Experimental contrast dye that is commonly used as a visualization aid in pelvic and abdominal surgeries and for various diagnostic procedures in medical practice.” NCT06054880 ↗
Modality	Small molecule	— CHEMBL1091250 ↗
Route	Oral	“indigo carmine ingested orally mixed with the standard colonoscopy prep” NCT01901510 ↗