Drugs / HRS-1167
last change Jun 2026 re-read 2 minutes ago

HRS-1167

also known as M9466

targets PARP1 via inhibition

Developed for
neoplasm · cancer · prostate cancer · Her2-receptor negative breast cancer · ovarian cancer
Investigated by
Jiangsu HengRui Medicine Co., Ltd. · EMD Serono Research & Development Institute, Inc. · Merck KGaA, Darmstadt, Germany · Fudan University

Trials 9 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 15 trials
Phase 1 NCT06719973 May 2025 cancer EMD Serono Research & Development Institute, Inc. Withdrawn No outcome recorded
Phase 1 NCT06509906 Oct 2024 → Dec 2025 neoplasm EMD Serono Research & Development Institute, Inc. Terminated No outcome recorded
Phase 1 NCT06421935 Aug 2024 → Feb 2027 expected neoplasm EMD Serono Research & Development Institute, Inc. Active not recruiting No outcome recorded
Phase 1 NCT06198556 Jan → Feb 2024 neoplasm Jiangsu HengRui Medicine Co., Ltd. Completed No outcome recorded
Phase 1 NCT05473624 Aug 2022 → Dec 2026 expected cancer Jiangsu HengRui Medicine Co., Ltd. Recruiting No outcome recorded
Phase 1/23 trials
Phase 1/2 NCT06689163 Dec 2024 → Nov 2025 overdue prostate cancer Jiangsu HengRui Medicine Co., Ltd. Recruiting No outcome recorded
Phase 1/2 NCT06568094 Sep 2024 → Jun 2026 overdue prostate cancer Jiangsu HengRui Medicine Co., Ltd. Recruiting No outcome recorded
Phase 1/2 NCT06308406 Mar 2024 → Oct 2025 ovarian cancer Jiangsu HengRui Medicine Co., Ltd. Unknown No outcome recorded
Phase 21 trial
Phase 2 NCT06516289 Sep 2024 → Jun 2026 overdue Her2-receptor negative breast cancer Fudan University Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 9 sources stand behind the page.

FieldValueCited text
Known as HRS-1167 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05473624
5

NCT06689163

NCT06198556

NCT06516289

NCT06568094

NCT06308406

Known as M9466 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06509906
2

NCT06719973

NCT06421935

Action Inhibit “PARP1 Inhibitor M9466” NCT06421935
Route Oral “single oral dose of HRS-1167” NCT06198556
Target PARP1 PARP1 Inhibitor M9466” NCT06421935