Drugs / HER3-DXd

Trials 6

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT04676477 Jun 2021 → Jan 2025 overdue non-small cell lung carcinoma Daiichi Sankyo Active not recruiting No outcome recorded
Phase 1/22 trials
Phase 1/2 NCT06445972 Aug 2024 → May 2028 expected esophageal cancer, gastroesophageal adenocarcinoma, gastroesophageal junction adenocarcinoma Merck Sharp & Dohme LLC Recruiting No outcome recorded
Phase 1/2 NCT04165070 Dec 2019 → Feb 2032 expected non-small cell lung carcinoma Merck Sharp & Dohme LLC Recruiting No outcome recorded
Phase 22 trials
Phase 2 NCT06731907 Mar 2025 → Mar 2032 expected non-small cell lung carcinoma Merck Sharp & Dohme LLC Recruiting No outcome recorded
Phase 2 NCT06172478 Feb 2024 → Sep 2027 expected breast cancer, carcinoma of esophagus, cervical cancer, endometrial cancer +7 Daiichi Sankyo Recruiting No outcome recorded
Phase not stated1 trial
— NCT06099639 — lung cancer Daiichi Sankyo No longer available No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as HER3-DXd ClinicalTrials.gov intervention name — accepted as the source's own label NCT04165070 ↗
5

NCT04676477 ↗

NCT06099639 ↗

NCT06731907 ↗

NCT06172478 ↗

NCT06445972 ↗

Modality Monoclonal antibody “anti-HER3 monoclonal antibody” PMID 41088723 ↗ Oct 2025
Route Intravenous “IV Infusion” NCT04165070 ↗