Drugs / Telatinib
last change Oct 2025 re-read 3 minutes ago

Telatinib

also known as BAY 57-9352

Small molecule targets FLT4, KDR, KIT, PDGFRB via inhibition

Developed for
gastric cancer · cancer · hepatocellular carcinoma
Investigated by
ACT Biotech, Inc · Andrew Hendifar, MD · EOC Pharma · Fountain Medical Development Co., Ltd. · Taizhou EOC Pharma Co., Ltd.

Trials 3

2009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT03175497 Jul 2017 → Aug 2018 cancer Taizhou EOC Pharma Co., Ltd. Completed No outcome recorded
Phase 22 trials
Phase 2 NCT04798781 Jul 2021 → Feb 2024 gastric cancer, hepatocellular carcinoma Andrew Hendifar, MD Completed No outcome recorded
Phase 2 NCT00952497 Jun 2009 → Oct 2011 gastric cancer ACT Biotech, Inc Completed No outcome recorded
Comparator or background therapy1 trial
Phase 2 NCT03817411 Comparator Jan 2019 → Mar 2020 gastric cancer Taizhou EOC Pharma Co., Ltd. Unknown No outcome recorded

Evidence & citations 9 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Telatinib ClinicalTrials.gov intervention name — accepted as the source's own label NCT03817411 ↗
3

NCT03175497 ↗

NCT00952497 ↗

NCT04798781 ↗

Known as BAY 57-9352 ChEMBL registry synonym — accepted as the source's own label CHEMBL2079588 ↗
Action Inhibit “Vascular endothelial growth factor receptor 2 inhibitor” CHEMBL2079588 ↗
3

“Vascular endothelial growth factor receptor 3 inhibitor” CHEMBL2079588 ↗

“Platelet-derived growth factor receptor beta inhibitor” CHEMBL2079588 ↗

“Stem cell growth factor receptor inhibitor” CHEMBL2079588 ↗

Modality Small molecule — CHEMBL2079588 ↗
Route Oral “Telatinib (3 tablets) will be administered orally” NCT00952497 ↗
Target FLT4 “Vascular endothelial growth factor receptor 3 inhibitor” CHEMBL2079588 ↗
Target KDR “Vascular endothelial growth factor receptor 2 inhibitor” CHEMBL2079588 ↗
Target KIT “Stem cell growth factor receptor inhibitor” CHEMBL2079588 ↗
Target PDGFRB “Platelet-derived growth factor receptor beta inhibitor” CHEMBL2079588 ↗