Drugs / Brivoligide
last change Feb 2022 re-read 3 minutes ago

Brivoligide

also known as AYX1 · Brivoligida

targets EGR1 via inhibition

Developed for
neuropathy, painful
Investigated by
Adynxx, Inc. · National Institute on Drug Abuse (NIDA)

Trials 5

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT03797612 Jan 2021 → Jan 2022 neuropathy, painful Adynxx, Inc. Withdrawn No outcome recorded
Phase 2 NCT04104919 Jan 2021 → Jan 2022 — Adynxx, Inc. Withdrawn No outcome recorded
Phase 2 NCT02807428 Feb → Oct 2017 — Adynxx, Inc. Completed No outcome recorded
Phase 2 NCT02081703 May 2014 → Jun 2015 — Adynxx, Inc. Completed No outcome recorded
Phase 2 NCT01731730 Jan → Oct 2013 — Adynxx, Inc. Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as Brivoligide “6 mL solution for intrathecal injection with 660 mg of AYX1 (Brivoligide)” NCT02807428 ↗
2

NCT03797612 ↗

NCT04104919 ↗

Known as AYX1 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02081703 ↗
2

NCT01731730 ↗

NCT02807428 ↗

Known as Brivoligida ChEMBL registry synonym — accepted as the source's own label CHEMBL4297228 ↗
Action Inhibit “Early growth response protein 1 inhibitor” CHEMBL4297228 ↗
Route Intrathecal “3mL solution for intrathecal injection with 110 mg of AYX1” NCT01731730 ↗
Target EGR1 “Early growth response protein 1 inhibitor” CHEMBL4297228 ↗