Drugs / PKI-179
last change Feb 2012 re-read 3 minutes ago

PKI-179

Small molecule targets MTOR, PIK3CA via inhibition

Developed for
cancer
Investigated by
Wyeth is now a wholly owned subsidiary of Pfizer

Trials 1

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT00997360 Feb 2010 → Feb 2012 cancer Wyeth is now a wholly owned subsidiary of Pfizer Withdrawn No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as PKI-179 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00997360 ↗
Action Inhibit “Serine/threonine-protein kinase mTOR inhibitor” CHEMBL1258517 ↗
1

“PI3-kinase p110-alpha subunit inhibitor” CHEMBL1258517 ↗

Modality Small molecule — CHEMBL1258517 ↗
Route Oral “All subjects will receive daily oral dosing of PKI-179.” NCT00997360 ↗
Target MTOR “Serine/threonine-protein kinase mTOR inhibitor” CHEMBL1258517 ↗
Target PIK3CA “PI3-kinase p110-alpha subunit inhibitor” CHEMBL1258517 ↗