Drugs / CAR-T cells
Trials 28
Evidence & citations 10 cited values
Every value below carries the sentence it was read from. 30 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | CAR-T cells | “Subjects will receive (0.6-60)x10E8 transduced CART cells as a split dose over three days as follows: Day 0, 10% fraction: (0.06-6)x10E8 CART19 cells, Day 1, 30% fraction:...” NCT03767725 ↗28“a novel method for treatment of multiple myeloma, in which patients' T cells are engineered into B Cell Maturation Antigen（BMCA）-Targeted CAR-T cells to eliminate myeloma cells.” NCT03931421 ↗ “This intervention involves the infusion of autologous or allogeneic CAR-T cells into patients with relapsed/refractory hematologic malignancies.” NCT06849921 ↗ |
| Action | Deplete | “The trained cells are called CD30.CAR T cells. Then, the cells will be tested to make sure that they kill lymphoma cells that express the CD30 antigen and not normal cells.” NCT02917083 ↗ |
| Modality | Cell therapy | “chimeric antigen receptor (CAR)-modified T cells” NCT02186860 ↗ |
| Route | Intravenous | “a single dose of 1 million CAR-T cells per kg will be administrated intravenously” PMID 28039295 ↗ Dec 2016 |
| Target | AXL | “CAR-T cells targeting GPC3, Mesothelin, Claudin18.2, GUCY2C, B7-H3, PSCA, PSMA, MUC1, TGFβ, HER2, Lewis-Y, AXL, or EGFR” NCT03198052 ↗ |
| Target | EGFR | “CAR-T cells targeting GPC3, Mesothelin, Claudin18.2, GUCY2C, B7-H3, PSCA, PSMA, MUC1, TGFβ, HER2, Lewis-Y, AXL, or EGFR” NCT03198052 ↗ |
| Target | GPC3 | “CAR-T cells targeting GPC3, Mesothelin, Claudin18.2, GUCY2C, B7-H3, PSCA, PSMA, MUC1, TGFβ, HER2, Lewis-Y, AXL, or EGFR” NCT03198052 ↗ |
| Target | GUCY2C | “CAR-T cells targeting GPC3, Mesothelin, Claudin18.2, GUCY2C, B7-H3, PSCA, PSMA, MUC1, TGFβ, HER2, Lewis-Y, AXL, or EGFR” NCT03198052 ↗ |
| Target | MUC1 | “CAR-T cells targeting GPC3, Mesothelin, Claudin18.2, GUCY2C, B7-H3, PSCA, PSMA, MUC1, TGFβ, HER2, Lewis-Y, AXL, or EGFR” NCT03198052 ↗ |
| Target | PSCA | “CAR-T cells targeting GPC3, Mesothelin, Claudin18.2, GUCY2C, B7-H3, PSCA, PSMA, MUC1, TGFβ, HER2, Lewis-Y, AXL, or EGFR” NCT03198052 ↗ |