Drugs / GSK2330811
last change May 2025 re-read 3 minutes ago

GSK2330811

Monoclonal antibody targets OSM via inhibition

Developed for
systemic sclerosis · Crohn disease
Investigated by
GlaxoSmithKline

Trials 4

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT04138043 Dec 2019 → May 2020 — GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT02386436 Apr 2015 → Apr 2016 systemic sclerosis GlaxoSmithKline Completed No outcome recorded
Phase 22 trials
Phase 2 NCT04151225 Apr 2021 → Apr 2024 Crohn disease GlaxoSmithKline Withdrawn No outcome recorded Stop: Enrollment
Phase 2 NCT03041025 Jun 2017 → Jul 2020 systemic sclerosis GlaxoSmithKline Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as GSK2330811 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02386436 ↗
3

NCT04151225 ↗

NCT04138043 ↗

NCT03041025 ↗

Action Inhibit “blocks Oncostatin M (OSM)” NCT02386436 ↗
Modality Monoclonal antibody “an anti-OSM monoclonal antibody (GSK2330811) in healthy volunteers” PMID 38501358 ↗ Mar 2024
Route Subcutaneous “administered as single dose s.c.” NCT02386436 ↗
Target OSM “blocks Oncostatin M (OSM)” NCT02386436 ↗