Drugs / naratriptan
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | AMERGE | — | 1998-02-10 | fda.gov ↗ |
Trials 0
Also used as a comparator or background therapy in 6 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT03066544 Comparator | Nov 2016 → Dec 2019 | migraine disorder | Hartford HealthCare | Unknown | No outcome recorded |
| Phase 32 trials | ||||||
| Phase 3 | NCT01726920 Comparator | Jul → Dec 2014 | migraine disorder | Ache Laboratorios Farmaceuticos S.A. | Withdrawn | No outcome recorded |
| Phase 3 | NCT01390324 Comparator | Dec 2011 → Mar 2012 | migraine disorder | Ache Laboratorios Farmaceuticos S.A. | Withdrawn | No outcome recorded |
| Phase 43 trials | ||||||
| Phase 4 | NCT01086358 Comparator | Sep 2009 → Aug 2016 | — | The Cleveland Clinic | Completed | No outcome recorded |
| Phase 4 | NCT00282165 Comparator | Nov 2006 → Dec 2012 | antisocial personality disorder, intermittent explosive disorder, psychotic disorder | UMC Utrecht | Terminated | No outcome recorded |
| Phase 4 | NCT00487578 Comparator | Oct 2006 → Oct 2009 | — | Cady, Roger, M.D. | Terminated | No outcome recorded |
Evidence & citations 11 cited values
Every value below carries the sentence it was read from. 7 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | naratriptan | “Usual prescribed triptans may include:sumatriptan, rizatriptan, naratriptan, almotriptan, eletriptan, zolmitriptan” NCT01086358 ↗ |
| Known as | Amerge | ChEMBL registry synonym — accepted as the source's own label CHEMBL1278 ↗ |
| Known as | GR 85548A | ChEMBL registry synonym — accepted as the source's own label CHEMBL1278 ↗ |
| Known as | Naramig | ChEMBL registry synonym — accepted as the source's own label CHEMBL1278 ↗ |
| Known as | naratriptan HCl | “Drug: naratriptan HCl” NCT00487578 ↗ |
| Known as | NARATRIPTAN HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL1278 ↗ |
| Action | Activate | “Serotonin 1d (5-HT1d) receptor agonist” CHEMBL1278 ↗1“Serotonin 1b (5-HT1b) receptor agonist” CHEMBL1278 ↗ |
| Modality | Small molecule | — CHEMBL1278 ↗ |
| Route | Oral | “four weeks double blind experimental treatment using oral naratriptan” NCT00282165 ↗ |
| Target | HTR1B | “Serotonin 1b (5-HT1b) receptor agonist” CHEMBL1278 ↗ |
| Target | HTR1D | “Serotonin 1d (5-HT1d) receptor agonist” CHEMBL1278 ↗ |