Drugs / Ficonalkib
last change May 2026 re-read 2 minutes ago

Ficonalkib

also known as SY-3505

Small molecule targets ALK via inhibition

Developed for
non-small cell lung carcinoma · neoplasm
Investigated by
Shouyao Holdings (Beijing) Co. LTD

Trials 4 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT06037317 May 2024 → Dec 2025 neoplasm Shouyao Holdings (Beijing) Co. LTD Unknown No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT05257512 Apr 2020 → Apr 2024 non-small cell lung carcinoma Shouyao Holdings (Beijing) Co. LTD Unknown No outcome recorded
Phase 21 trial
Phase 2 NCT05869162 Jun 2023 → Jun 2025 non-small cell lung carcinoma Shouyao Holdings (Beijing) Co. LTD Unknown No outcome recorded
Phase 31 trial
Phase 3 NCT06254599 May 2024 → May 2026 overdue non-small cell lung carcinoma Shouyao Holdings (Beijing) Co. LTD Not yet recruiting No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Ficonalkib Ficonalkib (SY-3505) in Advanced ALK-Positive NSCLC: A Multicenter, Open-Label, Single-Arm, Phase 1/2 Study.” PMID 38295954 Jan 2024
Known as SY-3505 “Ficonalkib (SY-3505) in Advanced ALK-Positive NSCLC: A Multicenter, Open-Label, Single-Arm, Phase 1/2 Study.” PMID 38295954 Jan 2024
3

NCT05869162

NCT06037317

NCT06254599

Action Inhibit “a third-generation (3rd-gen) ALK TKI” PMID 38295954 Jan 2024
Modality Small molecule CHEMBL5314461
Route Oral “600 mg once daily (QD) orally” NCT05869162
Target ALK “a third-generation (3rd-gen) ALK TKI” PMID 38295954 Jan 2024