Drugs / Bovine Thrombin
Bovine Thrombin
Trials 2
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 21 trial · 1 met primary | ||||||
| Phase 2 | NCT02014402 | Dec 2013 → Nov 2015 | vascular hemostatic disease | Grifols | Completed | Met primary |
| Phase 31 trial · 1 met primary | ||||||
| Phase 3 | NCT00196534 | Nov 2004 → Jul 2006 | — | Ethicon, Inc. | Completed | Met primary |
| Comparator or background therapy1 trial | ||||||
| Phase 3 | NCT00245336 Comparator | Oct 2005 → Jun 2006 | — | ZymoGenetics | Completed | No outcome recorded |
Evidence & citations 7 cited values
Every value below carries the sentence it was read from. 7 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Bovine Thrombin | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00196534 ↗ |
| Known as | bovine plasma-derived thrombin | “This report examines the clinical results for the vascular surgery subgroup of patients enrolled in a larger double-blind, randomized, multicenter trial, which evaluated the...” PMID 18440754 ↗ Apr 2008 |
| Known as | bovine THROMBIN JMI | “evaluated the hemostatic efficacy and safety of plasma-derived topical thrombin (human) Grifols (TTH-Grifols; Instituto Grifols SA) vs bovine THROMBIN JMI (BT-JMI; GenTrac Inc)...” PMID 31376435 ↗ Jul 2019 |
| Known as | BT-JMI | “evaluated the hemostatic efficacy and safety of plasma-derived topical thrombin (human) Grifols (TTH-Grifols; Instituto Grifols SA) vs bovine THROMBIN JMI (BT-JMI; GenTrac Inc)...” PMID 31376435 ↗ Jul 2019 |
| Known as | bThrombin | “This report examines the clinical results for the vascular surgery subgroup of patients enrolled in a larger double-blind, randomized, multicenter trial, which evaluated the...” PMID 18440754 ↗ Apr 2008 |
| Modality | Protein / enzyme biologic | “Plasma-derived bovine thrombin is used as a topical agent to improve surgical hemostasis, but development of antibodies to bovine hemostatic proteins has been associated with...” PMID 17660072 ↗ Jun 2007 |
| Route | Topical | “human (n = 153) or bovine (n = 152) thrombin, applied topically with an absorbable gelatin sponge.” PMID 18241525 ↗ Jan 2008 |