Drugs / Terbogrel
last change Mar 2000 re-read 2 minutes ago

Terbogrel

also known as BIBV 308 SE

Small molecule targets TBXA2R, TBXAS1 via inhibition

Developed for
pulmonary hypertension
Investigated by
Boehringer Ingelheim

Trials 4 · a red edge is where a trial was stopped

199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT02222987 Feb → Mar 1999 Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT02223000 Mar → Jul 1998 Boehringer Ingelheim Completed No outcome recorded
Phase 22 trials
Phase 2 NCT02223494 Oct 1998 → Mar 2000 pulmonary hypertension Boehringer Ingelheim Terminated No outcome recorded
Phase 2 NCT02223481 May 1998 → Sep 1999 pulmonary hypertension Boehringer Ingelheim Completed No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02223013 Comparator Apr → May 1999 Boehringer Ingelheim Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as Terbogrel ClinicalTrials.gov intervention name — accepted as the source's own label NCT02223481
2

NCT02223494

NCT02222987

Known as BIBV 308 SE ClinicalTrials.gov intervention name — accepted as the source's own label NCT02223013
1

NCT02223000

Action Inhibit “Thromboxane A2 receptor antagonist” CHEMBL281398
1

“Thromboxane-A synthase inhibitor” CHEMBL281398

Modality Small molecule CHEMBL281398
Route Oral “Administered Orally” NCT02223000
Target TBXA2R “Thromboxane A2 receptor antagonist” CHEMBL281398
Target TBXAS1 “Thromboxane-A synthase inhibitor” CHEMBL281398