Drugs / Terbogrel
last change Mar 2000 re-read 9 days ago

Terbogrel

also known as BIBV 308 SE

Small molecule targets TBXA2R, TBXAS1 via inhibition

Developed for
pulmonary hypertension
Investigated by
Boehringer Ingelheim

Trials 4

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT02222987 Feb → Mar 1999 — Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT02223000 Mar → Jul 1998 — Boehringer Ingelheim Completed No outcome recorded
Phase 22 trials
Phase 2 NCT02223494 Oct 1998 → Mar 2000 pulmonary hypertension Boehringer Ingelheim Terminated No outcome recorded
Phase 2 NCT02223481 May 1998 → Sep 1999 pulmonary hypertension Boehringer Ingelheim Completed No outcome recorded
Comparator or background therapy1 trial
Phase 1 NCT02223013 Comparator Apr → May 1999 — Boehringer Ingelheim Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as Terbogrel ClinicalTrials.gov intervention name — accepted as the source's own label NCT02222987 ↗
2

NCT02223481 ↗

NCT02223494 ↗

Known as BIBV 308 SE ClinicalTrials.gov intervention name — accepted as the source's own label NCT02223000 ↗
1

NCT02223013 ↗

Action Inhibit “Thromboxane A2 receptor antagonist” CHEMBL281398 ↗
1

“Thromboxane-A synthase inhibitor” CHEMBL281398 ↗

Modality Small molecule — CHEMBL281398 ↗
Route Oral “Administered Orally” NCT02223000 ↗
Target TBXA2R “Thromboxane A2 receptor antagonist” CHEMBL281398 ↗
Target TBXAS1 “Thromboxane-A synthase inhibitor” CHEMBL281398 ↗