Drugs / BPI-9016
last change Nov 2024 re-read 3 minutes ago

BPI-9016

also known as BPI-9016M

Small molecule targets AXL, MET via inhibition

Developed for
cancer · non-small cell lung carcinoma
Investigated by
Betta Pharmaceuticals Co., Ltd.

Trials 2

201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02929290 Mar 2017 → Nov 2024 non-small cell lung carcinoma Betta Pharmaceuticals Co., Ltd. Unknown No outcome recorded
Phase 1 NCT02478866 Aug 2015 → Jun 2017 cancer Betta Pharmaceuticals Co., Ltd. Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as BPI-9016 ChEMBL registry synonym — accepted as the source's own label CHEMBL3545236 ↗
Known as BPI-9016M ClinicalTrials.gov intervention name — accepted as the source's own label NCT02929290 ↗
1

NCT02478866 ↗

Action Inhibit “BPI-9016M is a novel small-molecule inhibitor that simultaneously targets both c-Met and AXL tyrosine kinases.” PMID 31948451 ↗ Jan 2020
Modality Small molecule “BPI-9016M is a novel small-molecule inhibitor that simultaneously targets both c-Met and AXL tyrosine kinases.” PMID 31948451 ↗ Jan 2020
Route Oral “BPI-9016M administered orally once daily (QD)” NCT02478866 ↗
Target AXL “BPI-9016M is a novel small-molecule inhibitor that simultaneously targets both c-Met and AXL tyrosine kinases.” PMID 31948451 ↗ Jan 2020
Target MET “BPI-9016M is a novel small-molecule inhibitor that simultaneously targets both c-Met and AXL tyrosine kinases.” PMID 31948451 ↗ Jan 2020