Drugs / INETAGUGENE GEPERPAVEC
last change Mar 2025 re-read 3 minutes ago

INETAGUGENE GEPERPAVEC

also known as KB105 · HSV1-TGM1

targets TGM1

Developed for
autosomal recessive congenital ichthyosis · autosomal recessive congenital ichthyosis 1
Investigated by
Krystal Biotech, Inc.

Trials 2

2020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT04047732 Aug 2019 → Oct 2022 autosomal recessive congenital ichthyosis 1 Krystal Biotech, Inc. Unknown No outcome recorded
Phase 21 trial
Phase 2 NCT05735158 Mar 2023 → Mar 2024 autosomal recessive congenital ichthyosis Krystal Biotech, Inc. Unknown No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as INETAGUGENE GEPERPAVEC ChEMBL registry synonym — accepted as the source's own label CHEMBL4650243 ↗
Known as HSV1-TGM1 “HSV1-TGM1 vector (KB105)” NCT04047732 ↗
Known as KB105 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04047732 ↗
1

NCT05735158 ↗

Route Topical “topically administered KB105” NCT04047732 ↗
Target TGM1 “expressing human transglutaminase 1 (TGM1)” NCT04047732 ↗