Drugs / Multimeric-001
last change Oct 2020 re-read 2 minutes ago

Multimeric-001

also known as M-001

Vaccine

Developed for
influenza
Investigated by
BiondVax Pharmaceuticals ltd. · National Institute of Allergy and Infectious Diseases (NIAID) · Seventh Framework Programme

Trials 8 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/22 trials
Phase 1/2 NCT01010737 Sep 2009 → Mar 2010 influenza BiondVax Pharmaceuticals ltd. Completed No outcome recorded
Phase 1/2 NCT00877448 Jun → Oct 2009 BiondVax Pharmaceuticals ltd. Completed No outcome recorded
Phase 25 trials
Phase 2 NCT03058692 Apr 2018 → Jan 2019 influenza National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 2 NCT02691130 Nov 2015 → Oct 2016 influenza BiondVax Pharmaceuticals ltd. Completed No outcome recorded
Phase 2 NCT02293317 Nov 2014 → Mar 2015 influenza BiondVax Pharmaceuticals ltd. Completed No outcome recorded
Phase 2 NCT01419925 Aug 2011 → Jan 2012 influenza BiondVax Pharmaceuticals ltd. Completed No outcome recorded
Phase 2 NCT01146119 Jul 2010 → May 2011 influenza BiondVax Pharmaceuticals ltd. Completed No outcome recorded
Phase 31 trial
Phase 3 NCT03450915 Aug 2018 → Jul 2020 influenza BiondVax Pharmaceuticals ltd. Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 10 sources stand behind the page.

FieldValueCited text
Known as Multimeric-001 “Two Doses of Multimeric-001 (M-001) Followed by Influenza Vaccine” NCT03058692
5

NCT02691130

NCT01146119

NCT01419925

NCT01010737

NCT00877448

Known as M-001 “A new vaccine, "Multimeric-001" (M-001) has been recently developed, containing conserved, common linear influenza epitopes that activate both cellular and humoral arms of the...” PMID 25173483 Aug 2014
5

“Multimeric-001 (M-001) was administered twice at a dose of 250mcg via the IM route to 10 participants as a primer, followed by TIV boost immunization.” NCT01010737

“The M-001 vaccine consists of 3 repetitions of 9 conserved linear epitopes that are prepared as a single recombinant protein.” NCT03058692

“Multimeric 001 (M-001)” NCT02691130

NCT03450915

NCT02293317

Modality Vaccine “A new vaccine, Multimeric-001, containing conserved linear epitopes from the HA, NP, and M1 proteins of influenza type A and type B strains was designed to protect against...” PMID 22318394 Feb 2012
Route Intramuscular “Two intramuscular injections were administered, 21 days apart.” PMID 22318394 Feb 2012