Drugs / FLETIKUMAB
Trials 6 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 13 trials | ||||||
| Phase 1 | NCT01038674 | Feb → Dec 2010 | rheumatoid arthritis | Novo Nordisk A/S | Completed | No outcome recorded |
| Phase 1 | NCT00818064 | Dec 2008 → Jan 2010 | rheumatoid arthritis | Novo Nordisk A/S | Completed | No outcome recorded |
| Phase 1 | NCT01261767 | Apr 2008 → Jan 2011 | psoriasis | Novo Nordisk A/S | Terminated | No outcome recorded |
| Phase 23 trials | ||||||
| Phase 2 | NCT02097264 | Sep 2014 → Sep 2015 | rheumatoid arthritis | Novo Nordisk A/S | Withdrawn | No outcome recorded |
| Phase 2 | NCT01636843 | Oct 2012 → Nov 2014 | rheumatoid arthritis | Novo Nordisk A/S | Terminated | No outcome recorded |
| Phase 2 | NCT01636817 | Aug 2012 → Nov 2014 | rheumatoid arthritis | Novo Nordisk A/S | Terminated | No outcome recorded |
Evidence & citations 7 cited values
Every value below carries the sentence it was read from. 6 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | FLETIKUMAB | ChEMBL registry synonym — accepted as the source's own label CHEMBL3301580 ↗ |
| Known as | Anti-IL-20 | ChEMBL registry synonym — accepted as the source's own label CHEMBL3301580 ↗ |
| Known as | NNC0109-0012 | “NNC0109-0012, a novel human monoclonal antibody that binds to and neutralizes the activity of interleukin-20, was investigated as a potential treatment for inflammatory diseases.” PMID 25749867 ↗ Mar 20154“recombinant monoclonal anti-interleukin-20 (IL-20) antibody, NNC0109-0012” PMID 26252485 ↗ Aug 2015 |
| Action | Inhibit | “binds to and neutralizes the activity of interleukin-20” PMID 25749867 ↗ Mar 2015 |
| Modality | Monoclonal antibody | “NNC0109-0012, a novel human monoclonal antibody” PMID 25749867 ↗ Mar 2015 |
| Route | Subcutaneous | “NNC0109-0012 was administered subcutaneously” PMID 25749867 ↗ Mar 2015 |
| Target | IL20 | “binds to and neutralizes the activity of interleukin-20” PMID 25749867 ↗ Mar 2015 |