Drugs / TERN-101
last change Jun 2025 re-read 3 minutes ago

TERN-101

also known as LY-2562175

Small molecule targets NR1H4 via activation

Developed for
metabolic dysfunction-associated steatohepatitis
Investigated by
Terns, Inc.

Trials 2

202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT05415722 Jun 2022 → Jul 2023 metabolic dysfunction-associated steatohepatitis Terns, Inc. Completed Met primary
Phase 2 NCT04328077 Jun 2020 → May 2021 metabolic dysfunction-associated steatohepatitis Terns, Inc. Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as TERN-101 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04328077 ↗
1

NCT05415722 ↗

Known as LY-2562175 ChEMBL registry synonym — accepted as the source's own label CHEMBL3746388 ↗
Action Activate “TERN-101 (farnesoid X receptor agonist)” PMID 40500414 ↗ Jun 2025
1

“Bile acid receptor FXR agonist” CHEMBL3746388 ↗

Modality Small molecule — CHEMBL3746388 ↗
Route Oral “Orally administered.” NCT04328077 ↗
Target NR1H4 “Bile acid receptor FXR agonist” CHEMBL3746388 ↗