Drugs / N-acetyl-aspartyl-glutamate
last change Mar 2024 re-read 2 minutes ago

N-acetyl-aspartyl-glutamate

also known as NAAGA

Peptide

Developed for
atopic conjunctivitis · dry eye syndrome
Investigated by
Azienda Ospedaliera OO.RR. S. Giovanni di Dio e Ruggi D'Aragona

Trials 1 · a red edge is where a trial was stopped

202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 4 NCT06800274 Apr 2023 → Mar 2024 atopic conjunctivitis, dry eye syndrome Azienda Ospedaliera OO.RR. S. Giovanni di Dio e Ruggi D'Aragona Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as N-acetyl-aspartyl-glutamate “This randomized, single-blind study aims to compare the efficacy and safety of N-acetyl-aspartyl-glutamate (NAAGA) and azelastine hydrochloride eye drops in patients with...” NCT06800274
Known as NAAGA ClinicalTrials.gov intervention name — accepted as the source's own label NCT06800274
Action Inhibit “reducing histamine release and mitigating inflammatory cascades such as leukotriene production and complement activation.” NCT06800274
Modality Peptide “NAAGA is a neuropeptide with dual activity as a mast cell stabilizer and anti-inflammatory agent” NCT06800274
Route Other “80 patients were randomly assigned to NAAGA in single dose (49 mg/mL), instilled as 1 drop per eye four times daily for four weeks.” NCT06800274