Drugs / camicinal
last change Dec 2017 re-read 2 minutes ago

camicinal

also known as GSK962040 · GSK-962040B

Small molecule targets MLNR via activation

Developed for
gastroparesis
Investigated by
GlaxoSmithKline

Trials 11 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 15 trials
Phase 1 NCT01366560 Aug → Oct 2010 intestinal motility disease GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT01267071 Jun → Sep 2010 gastroparesis GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT01039974 Sep → Nov 2009 gastroparesis GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT00733551 Sep 2008 → Jul 2009 gastroparesis GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT00562848 Sep 2007 → Jun 2008 gastroparesis GlaxoSmithKline Completed No outcome recorded
Phase 26 trials
Phase 2 NCT02210000 Aug 2014 → Aug 2015 gastroparesis GlaxoSmithKline Completed No outcome recorded
Phase 2 NCT01934192 Apr 2014 → Jul 2016 gastroparesis GlaxoSmithKline Terminated No outcome recorded
Phase 2 NCT01602549 Jul 2012 → May 2014 gastroparesis GlaxoSmithKline Completed No outcome recorded
Phase 2 NCT01262898 May 2011 → Feb 2013 gastroparesis GlaxoSmithKline Completed No outcome recorded
Phase 2 NCT01039805 Dec 2009 → Jul 2011 gastroparesis GlaxoSmithKline Completed No outcome recorded
Phase 2 NCT00861809 Jun 2009 → Nov 2010 gastroparesis GlaxoSmithKline Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 14 sources stand behind the page.

FieldValueCited text
Known as camicinal “We evaluated the effect of camicinal (GSK962040), a gastroprokinetic, on the absorption of l-dopa and symptoms of PD.” PMID 29278279 Dec 2017
3

“the novel gastric promotility agent motilin agonist camicinal (GSK962040) in critically ill feed-intolerant patients” PMID 27476581 Aug 2016

“Manometric evaluation of the motilin receptor agonist camicinal (GSK962040) in humans.” PMID 28782145 Aug 2017

NCT02210000

Known as GSK-962040B ChEMBL registry synonym — accepted as the source's own label CHEMBL489095
Known as GSK962040 GSK962040 is a selective non-peptide motilin receptor agonist which is being developed for the treatment of conditions associated with slow rates of gastric emptying.” NCT01267071
9

“the novel gastric promotility agent motilin agonist camicinal (GSK962040) in critically ill feed-intolerant patients” PMID 27476581 Aug 2016

GSK962040 is a selective non-peptide motilin receptor agonist” NCT01366560

NCT01039974

NCT00562848

NCT01262898

NCT00733551

NCT01934192

NCT00861809

NCT01602549

Action Activate “Camicinal (GSK962040), a small molecule motilin receptor agonist” PMID 28782145 Aug 2017
1

“Motilin receptor agonist” CHEMBL489095

Modality Small molecule “Camicinal (GSK962040), a small molecule motilin receptor agonist, has been shown to increase gastrointestinal motility.” PMID 28782145 Aug 2017
Route Oral “the Oral Motilin Receptor Agonist GSK962040” NCT00562848
Target MLNR “Motilin receptor agonist” CHEMBL489095