Drugs / Moclobemide
last change Jan 2018 re-read 2 minutes ago

Moclobemide

Small molecule targets MAOA via inhibition

Developed for
nicotine dependence · substance dependence
Investigated by
China Medical University Hospital · Hannover Medical School · Jed E. Rose · National Institute on Drug Abuse (NIDA) · Philip Morris USA

Trials 3 · a red edge is where a trial was stopped

20142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 22 trials
Phase 2 NCT03010761 Jan 2016 → Jan 2018 substance dependence China Medical University Hospital Terminated No outcome recorded
Phase 2 NCT01926626 Sep 2013 → Jul 2014 nicotine dependence Jed E. Rose Completed No outcome recorded
Phase 31 trial
Phase 3 NCT02374567 Jan 2015 → Jun 2017 anxiety disorder, dementia, depressive disorder, schizophrenia +1 Hannover Medical School Terminated No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 3 NCT00534573 Comparator Nov 2008 → Jan 2009 Beersheva Mental Health Center Completed No outcome recorded

Evidence & citations 9 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Moclobemide ClinicalTrials.gov intervention name — accepted as the source's own label NCT00534573
3

NCT03010761

NCT01926626

NCT02374567

Known as Aurorix ChEMBL registry synonym — accepted as the source's own label CHEMBL86304
Known as GNF-PF-695 ChEMBL registry synonym — accepted as the source's own label CHEMBL86304
Known as Manerix ChEMBL registry synonym — accepted as the source's own label CHEMBL86304
Known as Moclobemida ChEMBL registry synonym — accepted as the source's own label CHEMBL86304
Known as RO 11-1163/000 ChEMBL registry synonym — accepted as the source's own label CHEMBL86304
Action Inhibit “moclobemide, a selective, reversible MAO-A inhibitor” NCT01926626
1

“Monoamine oxidase A inhibitor” CHEMBL86304

Modality Small molecule CHEMBL86304
Target MAOA “Monoamine oxidase A inhibitor” CHEMBL86304