Drugs / Triclabendazole
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Triclabendazole

Small molecule

Developed for
fascioliasis · parasitic infectious disease
Investigated by
Novartis Pharmaceuticals · University of Colorado, Denver

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) EGATEN 2019-02-13 fda.gov

Trials 2 · a red edge is where a trial was stopped

today
US approved 2019
NCT04230148 · Ph 4
20192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 41 trial
Phase 4 NCT04230148 Feb 2022 → Mar 2026 fascioliasis Novartis Pharmaceuticals Completed No outcome recorded
Phase not stated1 trial
NCT01931085 parasitic infectious disease University of Colorado, Denver No longer available No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT06367361 Comparator Aug 2026 → Apr 2029 expected fascioliasis Universidad Peruana Cayetano Heredia Not yet recruiting No outcome recorded

Press releases naming this drug 2 releases

DateIssuerRelease
2019-02-13 Novartis Pharmaceuticals Novartis receives FDA approval for Egaten® for the treatment of fascioliasis, a neglected tropical disease novartis.com
2018-07-23 Novartis Pharmaceuticals Novartis renews drug donation of Egaten® (triclabendazole) until 2022, reaffirming its commitment to the fight against liver fluke novartis.com

Evidence & citations 10 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Triclabendazole ClinicalTrials.gov intervention name — accepted as the source's own label NCT01931085
2

NCT04230148

NCT06367361

Known as EGA230B ChEMBL registry synonym — accepted as the source's own label CHEMBL1086440
Known as Egaten Egaten (Triclabendazole) 250 mg tablets” NCT04230148
Known as Egaten tm ChEMBL registry synonym — accepted as the source's own label CHEMBL1086440
Known as Fasinex ChEMBL registry synonym — accepted as the source's own label CHEMBL1086440
Known as NSC-759250 ChEMBL registry synonym — accepted as the source's own label CHEMBL1086440
Known as NVP-EGA230 ChEMBL registry synonym — accepted as the source's own label CHEMBL1086440
Known as Triclabendazol ChEMBL registry synonym — accepted as the source's own label CHEMBL1086440
Modality Small molecule “Triclabendazole is a benzimidazole compound used as a systemic antihelmintic in veterinary practice.” NCT01931085
Route Oral “Egaten 250 mg scored tablets for oral use.” NCT04230148