Drugs / FH-WT1-E50 TCR T
last change Aug 2026 re-read 2 minutes ago

FH-WT1-E50 TCR T

Cell therapy targets WT1 via depletion

Developed for
acute myeloid leukemia
Investigated by
Fred Hutchinson Cancer Center · National Cancer Institute (NCI)

Trials 1 · a red edge is where a trial was stopped

2027202820292030
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT07645469 Aug 2026 → Jul 2030 expected acute myeloid leukemia Fred Hutchinson Cancer Center Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as FH-WT1-E50 TCR T “If additional cells are available patients may receive a second infusion of azacitidine IV followed by FH-WT1-E50 TCR T cells IV, starting at 28 days, up to 1 year.” NCT07645469
Action Deplete “T cells are infection fighting blood cells that can kill tumor cells.” NCT07645469
Modality Cell therapy “The T cells given in this study will come from the patient and will have a new gene put in them that makes them able to recognize WT1” NCT07645469
Route Intravenous “Given IV” NCT07645469
Target WT1 “recognize WT1, a protein on the surface of cancer cells” NCT07645469