Drugs / AT278
last change Aug 2026 re-read 9 days ago

AT278

also known as insulin aspart

Protein / enzyme biologic

Developed for
type 2 diabetes mellitus
Investigated by
Arecor Limited

Trials 1

202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05754424 Feb 2023 → Jan 2024 type 2 diabetes mellitus Arecor Limited Completed No outcome recorded

News releases announcing trial results or a regulatory action · 2

DateIssuerRelease
2026-08-13 Arecor Limited Results Peer-Reviewed Publication of AT278 Study in Diabetes, Obesity and Metabolism journal arecor.com ↗
AT278 exhibited a significantly faster insulin absorption than both standard U100 concentration insulin aspart and U500 human regular insulin.
2026-07-30 Arecor Limited Results Diabetes, Obesity and Metabolism article – A New Highly Concentrated Insulin Aspart AT278 (500 U/mL) Demonstrates Ultra-Rapid Pharmacokinetic and Pharmacodynamic Properties in Type 2 Diabetes Regardless of BMI arecor.com ↗
A New Highly Concentrated Insulin Aspart AT278 (500 U/mL) Demonstrates Ultra-Rapid Pharmacokinetic and Pharmacodynamic Properties in Type 2 Diabetes Regardless of BMI

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as AT278 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05754424 ↗
Known as insulin aspart “This is a phase 1, single dose, randomised, double-blind, two-way crossover study to compare ultra-rapid-acting concentrated insulin aspart AT278 (U500/mL) with standard...” NCT05754424 ↗
Modality Protein / enzyme biologic “Concentrated rapid acting insulin aspart” NCT05754424 ↗
Route Subcutaneous “Single subcutaneous injection of 0.5 U/kg” NCT05754424 ↗