Drugs / tibremciclib
last change Dec 2025 re-read 2 minutes ago

tibremciclib

also known as BPI-16350

Small molecule targets CDK4 via inhibition

Developed for
breast cancer · cancer
Investigated by
Betta Pharmaceuticals Co., Ltd.

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT05316259 Apr → Aug 2022 Betta Pharmaceuticals Co., Ltd. Completed No outcome recorded
Phase 1 NCT03791112 Jul 2019 → Dec 2025 overdue cancer Betta Pharmaceuticals Co., Ltd. Active not recruiting No outcome recorded
Phase 31 trial
Phase 3 NCT05433480 May 2022 → Dec 2023 breast cancer Betta Pharmaceuticals Co., Ltd. Unknown No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as tibremciclib Tibremciclib (BPI-16350) is a novel potent selective inhibitor of cyclin-dependent kinase 4 and 6 (CDK4/6).” PMID 40403388 May 2025
Known as BPI-16350 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05316259
2

NCT03791112

NCT05433480

Action Inhibit “novel potent selective inhibitor of cyclin-dependent kinase 4 and 6 (CDK4/6)” PMID 40403388 May 2025
Modality Small molecule CHEMBL5314545
Route Oral “BPI-16350 capsules administered orally” NCT03791112
Target CDK4 “novel potent selective inhibitor of cyclin-dependent kinase 4 and 6 (CDK4/6)” PMID 40403388 May 2025