Drugs / BIIB023
last change Jan 2016 re-read 3 minutes ago

BIIB023

Monoclonal antibody targets TNFSF12 via inhibition

Developed for
lupus nephritis · rheumatoid arthritis
Investigated by
Biogen

Trials 5

2009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT01943513 Oct 2013 → Jan 2014 — Biogen Completed No outcome recorded
Phase 1 NCT01407406 Sep 2011 → Feb 2012 — Biogen Completed No outcome recorded
Phase 1 NCT00771329 Oct 2008 → Apr 2011 rheumatoid arthritis Biogen Completed No outcome recorded
Phase 22 trials
Phase 2 NCT01930890 Nov 2013 → Jan 2016 lupus nephritis Biogen Terminated No outcome recorded
Phase 2 NCT01499355 Jul 2012 → Dec 2015 lupus nephritis Biogen Terminated No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as BIIB023 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01407406 ↗
4

NCT01499355 ↗

NCT01943513 ↗

NCT01930890 ↗

NCT00771329 ↗

Action Inhibit “Tumor necrosis factor ligand superfamily member 12 inhibitor” CHEMBL2109598 ↗
1

“TWEAK-blocking monoclonal antibody BIIB023” PMID 23928094 ↗ Aug 2013

Modality Monoclonal antibody “TWEAK-blocking monoclonal antibody BIIB023” PMID 23928094 ↗ Aug 2013
Route Intravenous “administered intravenously” NCT00771329 ↗
Target TNFSF12 “Tumor necrosis factor ligand superfamily member 12 inhibitor” CHEMBL2109598 ↗