Drugs / LAM-002A
last change May 2025 re-read 3 minutes ago

LAM-002A

targets PIKFYVE via inhibition

Developed for
amyotrophic lateral sclerosis · frontotemporal dementia · lymphoid neoplasm
Investigated by
OrphAI Therapeutics

Trials 3

201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT02594384 Oct 2015 → Mar 2020 lymphoid neoplasm OrphAI Therapeutics Completed No outcome recorded
Phase 21 trial
Phase 2 NCT05163886 Dec 2021 → Jan 2023 amyotrophic lateral sclerosis OrphAI Therapeutics Completed No outcome recorded
Phase not stated1 trial
— NCT05483322 — frontotemporal dementia OrphAI Therapeutics No longer available No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as LAM-002A ClinicalTrials.gov intervention name — accepted as the source's own label NCT05483322 ↗
2

NCT02594384 ↗

NCT05163886 ↗

Action Inhibit “PIKfyve inhibitor” PMID 38606777 ↗ Sep 2024
Route Oral “administered by mouth” NCT02594384 ↗
Target PIKFYVE “PIKfyve inhibitor” PMID 38606777 ↗ Sep 2024