Drugs / TALMAPIMOD
last change Dec 2007 re-read 2 minutes ago

TALMAPIMOD

also known as SCIO-469

Small molecule targets MAPK14 via inhibition

Developed for
rheumatoid arthritis · plasma cell myeloma · myelodysplastic syndrome
Investigated by
Scios, Inc.

Trials 6 · a red edge is where a trial was stopped

2003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00508768 ? → Dec 2002 rheumatoid arthritis Scios, Inc. Completed No outcome recorded
Phase 25 trials
Phase 2 NCT00113893 May 2005 → Dec 2007 bone marrow neoplasm, myelodysplastic syndrome Scios, Inc. Completed No outcome recorded
Phase 2 NCT00095680 Nov 2004 → Feb 2006 plasma cell myeloma Scios, Inc. Completed No outcome recorded
Phase 2 NCT00089921 Jul 2004 → Oct 2005 rheumatoid arthritis Scios, Inc. Completed No outcome recorded
Phase 2 NCT00087867 Jun 2004 → Sep 2005 plasma cell myeloma Scios, Inc. Completed No outcome recorded
Phase 2 NCT00043732 ? → Sep 2003 rheumatoid arthritis Scios, Inc. Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as TALMAPIMOD ChEMBL registry synonym — accepted as the source's own label CHEMBL514201
Known as SCIO-469 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00113893
5

NCT00043732

NCT00508768

NCT00089921

NCT00095680

NCT00087867

Action Inhibit “MAP kinase p38 alpha inhibitor” CHEMBL514201
1

inhibit p38 kinase” NCT00043732

Modality Small molecule CHEMBL514201
Route Oral “Patients took SCIO-469 two capsules (60 mg) by mouth three times a day” NCT00087867
Target MAPK14 “MAP kinase p38 alpha inhibitor” CHEMBL514201