Drugs / BAY2287411
last change Mar 2022 re-read 3 minutes ago

BAY2287411

targets MSLN

Developed for
malignant peritoneal mesothelioma · ovarian serous adenocarcinoma · pleural epithelioid mesothelioma
Investigated by
Bayer

Trials 1

20192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03507452 Jun 2018 → Sep 2021 malignant peritoneal mesothelioma, ovarian serous adenocarcinoma, pancreatic ductal adenocarcinoma, pleural epithelioid mesothelioma Bayer Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as BAY 2287411 “We present herein the preclinical evaluation of a mesothelin (MSLN)-targeted thorium-227 conjugate, BAY 2287411.” PMID 31064781 ↗ May 2019
1

NCT03507452 ↗

Known as Anetumab corixetan thorium th-227 ChEMBL registry synonym — accepted as the source's own label CHEMBL4297906 ↗
Route Intravenous “A single dose will be administered intravenously on Day 1 of each cycle lasting 6 weeks (42 days).” NCT03507452 ↗
Target MSLN “a mesothelin (MSLN)-targeted thorium-227 conjugate, BAY 2287411” PMID 31064781 ↗ May 2019