Drugs / Dexanabinol
Dexanabinol
Trials 5 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 14 trials | ||||||
| Phase 1 | NCT02423239 | Apr 2015 → Dec 2016 | hepatocellular carcinoma, malignant exocrine pancreas neoplasm | e-Therapeutics PLC | Unknown | No outcome recorded |
| Phase 1 | NCT02054754 | Jan → Sep 2014 | cancer | e-Therapeutics PLC | Completed | No outcome recorded |
| Phase 1 | NCT01654497 | Jun 2012 → Sep 2015 | brain cancer | Santosh Kesari, M.D., Ph.D. | Completed | No outcome recorded |
| Phase 1 | NCT01489826 | Jan 2012 → Jul 2015 | cancer | e-Therapeutics PLC | Completed | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT00129857 | Jan 2001 → Sep 2004 | traumatic brain injury | Pharmos | Completed | No outcome recorded |
Evidence & citations 9 cited values
Every value below carries the sentence it was read from. 7 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Dexanabinol | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01489826 ↗ |
| Known as | HU-211 | ChEMBL registry synonym — accepted as the source's own label CHEMBL334533 ↗ |
| Known as | PA-50211 | ChEMBL registry synonym — accepted as the source's own label CHEMBL334533 ↗ |
| Known as | PRS-211007 | ChEMBL registry synonym — accepted as the source's own label CHEMBL334533 ↗ |
| Known as | PRS-211007-000 | ChEMBL registry synonym — accepted as the source's own label CHEMBL334533 ↗ |
| Known as | Sinnabidol | ChEMBL registry synonym — accepted as the source's own label CHEMBL334533 ↗ |
| Action | Inhibit | “It combines the ability to block NMDA receptors and neuroinflammatory cascades in the same molecule.” NCT00129857 ↗ |
| Modality | Small molecule | “dexanabinol, a synthetic cannabinoid analogue devoid of psychotropic activity” PMID 16361021 ↗ Jan 2006 |
| Route | Intravenous | “a single intravenous 150 mg dose of dexanabinol or placebo” PMID 16361021 ↗ Jan 2006 |