Drugs / EMICERFONT
last change Nov 2012 re-read 2 minutes ago

EMICERFONT

also known as GW876008 · GW-876008X

Small molecule targets CRHR1 via inhibition

Developed for
irritable bowel syndrome · social phobia
Investigated by
GlaxoSmithKline

Trials 10 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 16 trials
Phase 1 NCT00508911 Jun → Oct 2007 social phobia GlaxoSmithKline Terminated No outcome recorded
Phase 1 NCT00555139 Mar 2007 → Jan 2008 social phobia GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT00424697 Mar → Dec 2007 GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT00423761 Dec 2006 → ? GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT00376896 Nov 2006 → Oct 2008 irritable bowel syndrome GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT00429728 Nov 2006 → ? GlaxoSmithKline Completed No outcome recorded
Phase 24 trials
Phase 2 NCT00511563 Aug 2007 → Nov 2012 irritable bowel syndrome GlaxoSmithKline Withdrawn No outcome recorded
Phase 2 NCT00385099 Dec 2006 → Oct 2007 irritable bowel syndrome GlaxoSmithKline Completed No outcome recorded
Phase 2 NCT00397722 Nov 2006 → Sep 2007 social phobia GlaxoSmithKline Completed No outcome recorded
Phase 2 NCT00421707 Oct 2006 → Jun 2008 irritable bowel syndrome GlaxoSmithKline Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 11 sources stand behind the page.

FieldValueCited text
Known as EMICERFONT ChEMBL registry synonym — accepted as the source's own label CHEMBL514270
Known as GW-876008X ChEMBL registry synonym — accepted as the source's own label CHEMBL514270
Known as GW876008 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00385099
9

NCT00555139

NCT00423761

NCT00429728

NCT00508911

NCT00511563

NCT00424697

NCT00397722

NCT00376896

NCT00421707

Action Inhibit “Corticotrophin Releasing Factor 1 Receptor Antagonist (CRF1-RA)” NCT00376896
1

“Corticotropin releasing factor receptor 1 antagonist” CHEMBL514270

Modality Small molecule CHEMBL514270
Route Oral “single oral dose of GW876008” NCT00429728
Target CRHR1 “Corticotropin releasing factor receptor 1 antagonist” CHEMBL514270