drugset
Drugs / EMICERFONT
last change Nov 2012 re-read 9 days ago

EMICERFONT

also known as GW876008 · GW-876008X

Small molecule targets CRHR1 via inhibition

Developed for
irritable bowel syndrome · social phobia
Investigated by
GlaxoSmithKline

Trials 10

today NCT00511563 · Ph 2 NCT00508911 · Ph 1 NCT00555139 · Ph 1 NCT00424697 · Ph 1 NCT00423761 · Ph 1 NCT00385099 · Ph 2 NCT00376896 · Ph 1 NCT00429728 · Ph 1 NCT00397722 · Ph 2 NCT00421707 · Ph 2
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 16 trials
Phase 1 NCT00508911 Jun → Oct 2007 social phobia GlaxoSmithKline Terminated No outcome recorded
Phase 1 NCT00555139 Mar 2007 → Jan 2008 social phobia GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT00424697 Mar → Dec 2007 — GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT00423761 Dec 2006 → ? — GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT00376896 Nov 2006 → Oct 2008 irritable bowel syndrome GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT00429728 Nov 2006 → ? — GlaxoSmithKline Completed No outcome recorded
Phase 24 trials
Phase 2 NCT00511563 Aug 2007 → Nov 2012 irritable bowel syndrome GlaxoSmithKline Withdrawn No outcome recorded
Phase 2 NCT00385099 Dec 2006 → Oct 2007 irritable bowel syndrome GlaxoSmithKline Completed No outcome recorded
Phase 2 NCT00397722 Nov 2006 → Sep 2007 social phobia GlaxoSmithKline Completed No outcome recorded
Phase 2 NCT00421707 Oct 2006 → Jun 2008 irritable bowel syndrome GlaxoSmithKline Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 11 sources stand behind the page.

FieldValueCited text
Known as EMICERFONT ChEMBL registry synonym — accepted as the source's own label CHEMBL514270 ↗
Known as GW-876008X ChEMBL registry synonym — accepted as the source's own label CHEMBL514270 ↗
Known as GW876008 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00424697 ↗
9

NCT00376896 ↗

NCT00423761 ↗

NCT00385099 ↗

NCT00421707 ↗

NCT00397722 ↗

NCT00508911 ↗

NCT00511563 ↗

NCT00429728 ↗

NCT00555139 ↗
Action Inhibit “Corticotrophin Releasing Factor 1 Receptor Antagonist (CRF1-RA)” NCT00376896 ↗
1

“Corticotropin releasing factor receptor 1 antagonist” CHEMBL514270 ↗
Modality Small molecule — CHEMBL514270 ↗
Route Oral “single oral dose of GW876008” NCT00429728 ↗
Target CRHR1 “Corticotropin releasing factor receptor 1 antagonist” CHEMBL514270 ↗