Drugs / 23ME-00610
last change Mar 2025 re-read 3 minutes ago

23ME-00610

Monoclonal antibody targets CD200R1 via inhibition

Developed for
clear cell renal carcinoma · fallopian tube cancer · malignant epithelial tumor of ovary · primary peritoneal carcinoma · small cell lung carcinoma
Investigated by
23andMe, Inc.

Trials 1

20222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT05199272 Dec 2021 → Mar 2025 overdue clear cell renal carcinoma, fallopian tube cancer, malignant epithelial tumor of ovary, primary peritoneal carcinoma +1 23andMe, Inc. Active not recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as 23ME-00610 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05199272 ↗
Action Inhibit “23ME-00610 inhibits CD200R1 signaling” PMID 39651931 ↗ Jan 2025
Modality Monoclonal antibody “This phase 1 study of 23ME-00610, a CD200R1 antagonist IgG1, showed acceptable safety and tolerability, PK supporting Q3W dosing, and PD and preliminary clinical activity...” PMID 39651931 ↗ Jan 2025
Route Intravenous “23ME-00610 given by IV infusion” NCT05199272 ↗
Target CD200R1 “23ME-00610 inhibits CD200R1 signaling” PMID 39651931 ↗ Jan 2025