Drugs / BNT142
last change Dec 2025 re-read 3 minutes ago

BNT142

targets CLDN6

Developed for
cancer
Investigated by
BioNTech SE

Trials 1

2023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT05262530 Mar 2022 → Dec 2025 cancer BioNTech SE Terminated No outcome recorded Stop: Business

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2025-05-27 BioNTech SE Results BioNTech to Present Progress Across Diversified Oncology Pipeline at the 2025 ASCO Annual Meeting biontech.com ↗
Preliminary data indicated a manageable safety profile and early signs of clinical activity, supporting scientific proof-of-concept and underscoring the potential of mRNA-encoded bispecific antibodies.

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as BNT142 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05262530 ↗
Route Intravenous “Intravenous bolus/infusion” NCT05262530 ↗
Target CLDN6 “a T cell-engaging bispecific antibody that monovalently binds the T cell marker CD3 and bivalently binds claudin 6 (CLDN6), an oncofetal antigen” PMID 38776391 ↗ May 2024