Drugs / DOXEPIN
DOXEPIN
also known as
Doxepin hcl · DOXEPIN HYDROCHLORIDE · Doxepina · Doxepine · NSC-108160 · P-3693A · Quitaxon · Silenor · +4 more
Small molecule targets HRH1, SLC6A2 via inhibition
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | SILENOR | — | 2010-03-17 | fda.gov ↗ |
Trials 0
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Comparator or background therapy1 trial | ||||||
| Phase 4 | NCT02353299 Comparator | Jan 2015 → Jan 2016 | — | Currax Pharmaceuticals | Completed | No outcome recorded |
Press releases naming this drug 3 releases
| Date | Issuer | Release |
|---|---|---|
| 2023-03-28 | Zydus Lifesciences Limited | Zydus receives Final Approval from the USFDA for Doxepin Hydrochloride Capsules zyduslife.com ↗ |
| 2023-03-24 | Zydus Lifesciences Limited | Zydus receives final Approval from the USFDA for Doxepin Hydrochloride Capsules USP, 150 mg zyduslife.com ↗ |
| 2012-07-19 | Zydus Lifesciences Limited | Cadila Healthcare enters into a settlement and license agreement with Somaxon for Silenor zyduslife.com ↗ |
Evidence & citations 17 cited values
Every value below carries the sentence it was read from. 2 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | DOXEPIN | ChEMBL registry synonym — accepted as the source's own label CHEMBL1628227 ↗ |
| Known as | Doxepin hcl | ChEMBL registry synonym — accepted as the source's own label CHEMBL1628227 ↗ |
| Known as | DOXEPIN HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL1628227 ↗ |
| Known as | Doxepina | ChEMBL registry synonym — accepted as the source's own label CHEMBL1628227 ↗ |
| Known as | Doxepine | ChEMBL registry synonym — accepted as the source's own label CHEMBL1628227 ↗ |
| Known as | NSC-108160 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1628227 ↗ |
| Known as | P-3693A | ChEMBL registry synonym — accepted as the source's own label CHEMBL1628227 ↗ |
| Known as | Quitaxon | ChEMBL registry synonym — accepted as the source's own label CHEMBL1628227 ↗ |
| Known as | Silenor | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02353299 ↗ |
| Known as | Sinepin | ChEMBL registry synonym — accepted as the source's own label CHEMBL1628227 ↗ |
| Known as | Sinequan | ChEMBL registry synonym — accepted as the source's own label CHEMBL1628227 ↗ |
| Known as | Xepin | ChEMBL registry synonym — accepted as the source's own label CHEMBL1628227 ↗ |
| Known as | Zonalon | ChEMBL registry synonym — accepted as the source's own label CHEMBL1628227 ↗ |
| Action | Inhibit | “Norepinephrine transporter inhibitor” CHEMBL1628227 ↗1“Histamine H1 receptor antagonist” CHEMBL1628227 ↗ |
| Modality | Small molecule | — CHEMBL1628227 ↗ |
| Target | HRH1 | “Histamine H1 receptor antagonist” CHEMBL1628227 ↗ |
| Target | SLC6A2 | “Norepinephrine transporter inhibitor” CHEMBL1628227 ↗ |