Drugs / AL-78898A
last change Nov 2012 re-read 2 minutes ago

AL-78898A

targets C3 via inhibition

Developed for
age-related macular degeneration · diffuse secondary choroid atrophy · wet macular degeneration
Investigated by
Alcon Research · Potentia Pharmaceuticals, Inc.

Trials 3 · a red edge is where a trial was stopped

200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00473928 May 2007 → Feb 2010 age-related macular degeneration Potentia Pharmaceuticals, Inc. Completed No outcome recorded
Phase 22 trials
Phase 2 NCT01603043 Jun → Nov 2012 diffuse secondary choroid atrophy Alcon Research Terminated No outcome recorded
Phase 2 NCT01157065 Jun 2011 → Apr 2012 wet macular degeneration Alcon Research Completed No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Al-78898A ClinicalTrials.gov intervention name — accepted as the source's own label NCT01603043
1

NCT01157065

Known as (trp(me)4)-ac-compstatin ChEMBL registry synonym — accepted as the source's own label CHEMBL4594457
Known as 4(1mew) ChEMBL registry synonym — accepted as the source's own label CHEMBL4594457
Known as Compstatin analog 4(1mew) ChEMBL registry synonym — accepted as the source's own label CHEMBL4594457
Known as POT-4 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00473928
Action Inhibit “Complement C3 inhibitor” CHEMBL4594457
Route Intravitreal “Single intravitreal injection.” NCT00473928
Target C3 “Complement C3 inhibitor” CHEMBL4594457