Drugs / ACT-1004-1239
last change Jul 2024 re-read 3 minutes ago

ACT-1004-1239

targets ACKR3 via inhibition

Investigated by
Idorsia Pharmaceuticals Ltd.

Trials 3

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05549531 Oct 2022 — Idorsia Pharmaceuticals Ltd. Completed No outcome recorded
Phase 1 NCT04286750 Jul → Sep 2020 — Idorsia Pharmaceuticals Ltd. Completed No outcome recorded
Phase 1 NCT03869320 Mar → Jul 2019 — Idorsia Pharmaceuticals Ltd. Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as ACT-1004-1239 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05549531 ↗
2

NCT04286750 ↗

NCT03869320 ↗

Action Inhibit “ACT-1004-1239 is a potent, selective, insurmountable, and orally available first-in-class CXCR7 receptor antagonist.” PMID 33595155 ↗ Mar 2021
Route Oral “ACT-1004-1239 will be available for clinical study use as hard gelatin capsules for oral administration” NCT03869320 ↗
Target ACKR3 “ACT-1004-1239 is a potent and selective, first-in-class ACKR3/CXRC7 antagonist” PMID 39010703 ↗ Jul 2024